COMBO

Innovative Cultivation Methods for Marine Biodiscovery

Our mission is to address the supply challenges surrounding seaweed and sponge biomolecules by pioneering innovative cultivation techniques that leverage the holobiont concept.

Seaweeds

Our efforts will focus on harnessing the bioactive potential of phenolic metabolites of kelps and exploring the rich reservoir of terpenoids found in species belonging to the genera Dictyota and Laurencia, sourced from the Atlantic Ocean and the Mediterranean Sea. By strategically targeting these compounds, we aim to unlock their industrial applications.

Haliclona sarai and Crambe crambe

Sponges

Among the large diversity of bioactive metabolites produced by sponges, COMBO will target the polycyclic guanidine alkaloids produced by sponges of the family Crambeidae and the 3-alkylpyridine alkaloids characteristic of the Clade C of the order Haplosclerida.